What are Growth Factors?
- A naturally occurring substance in the human body
- Plays a key role in maintaining healthy skin structure and function
- Proteins that regulate cellular growth, proliferation, and differentiation under highly controlled conditions
- Secreted by all cell types that make up the epidermis and dermis: keratinocytes, fibroblasts, and melanocytes
Why are Growth Factors needed?
- Skin cells slow down their rate of growth and divisions as we age
- The collagen content of the skin decreases at a rate of approximately 1% a year
- As the degradation of collagen increases, it results in a 20% thinning of the dermis in the elderly
- The skin’s elastic fibers reduce in size causing less pliability and elasticity
How do Growth Factors work on the skin?
- Stimulate biochemical pathways to promote tissue repair and regeneration
- Promote the formation of elastic fibers and collagen which make skin soft and supple
What is the difference between Growth Factors and Stem Cells?
- Stem cells are undifferentiated cells of a multicellular organism that are capable of giving rise to indefinitely more cells of the same type, and from which certain other kinds of cells arise by differentiation
- Stem cells produce Growth Factors
- Growth Factors are proteins that signal cells and regulate cellular growth, proliferation and differentiation under highly controlled conditions
- Growth Factors are like a lock and key. A specific growth factor fits a specific receptor on the cell. Once attached, the growth factor signals the cell to start a specific action.
What is the difference between Peptides and Growth Factors?
- Growth Factors are a form of peptides
- Peptides are types of cytokines
- Cytokines are all types of molecules that signal or communicate to cells
- Growth Factors, chemically speaking belong to the same “family” as peptides, but the difference is the complexity and the job that each of them perform
- They are both chains of amino acids but peptides are shorter chains
Clinical Results- Controlled clinical studies with Growth Factor treatments have shown:
- Reduce skin roughness
- Improved skin texture and elasticity
- Reduce appearance of fine lines and tightness
Growth Factors have been used in wound healing since the 1990’s. Growth Factors need time to attach to cells and communicate. You will notice improved results over several days as the Growth Factors continue to work.
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